One hundred twenty five women were attending the antenatal clinic of Il Sin Christian Hospitla had a midtrimester amniocentesis between August 1990 and March 1993. The result were analized in reference to maternal age, indication, of
amniocentesis,
success rate and pregnancy outcome.
25. 6% were aged 35 and over significantly higher than the overall 2.7% for this age group.
The major indications were abnormal maternal serum alpha feto-protein 25.6%, previous chromosomal abnormality 22.4%, advanced maternal age 21.6%, previous fetal anomaly 16.0%.
The success rate of aspiration of amniotic fluid was 97.6% but culture rate of fetal cell was 88.7%.
The abnormal karyotypes were found in 4 cases(3.4%) that 3 cases of 9 inversion and 1 case of Turner syndrome.
The pregnancy outcome was full-term delivery 87.7%, premature delivery 1.3%, termination of pregnancy 5.5% and FDIU or spontaneous abortion 5.5%.
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